MAST Trimethoprim-Sulfamethoxazole 1.25-23.75µg Antibiotic Susceptibility Discs – 5 × 50 Discs

MAST Trimethoprim/Sulfamethoxazole 1.25/23.75µg Antibiotic Susceptibility Test Discs are high-quality antibiotic-impregnated paper discs designed for determining bacterial susceptibility to the combination of Trimethoprim and Sulfamethoxazole using standardized agar disc diffusion testing methods. Each disc contains 1.25 micrograms of Trimethoprim and 23.75 micrograms of Sulfamethoxazole, providing a combined antimicrobial potency of 25µg in a 1:19 ratio. Also known as Co-Trimoxazole, this antibiotic combination inhibits successive stages of bacterial folate synthesis. Sulfamethoxazole inhibits dihydropteroate synthase, while Trimethoprim inhibits dihydrofolate reductase. These discs support antimicrobial susceptibility investigations involving selected Gram-positive and Gram-negative bacterial pathogens, including Escherichia coli, Klebsiella species, Staphylococcus aureus and other organisms for which validated testing methods and interpretive criteria are available. Manufactured by MAST Group, the discs are suitable for hospital microbiology laboratories, clinical laboratories, diagnostic centres, medical research institutions and healthcare facilities conducting bacterial susceptibility testing. Key Features - Dual Antibiotic Combination: Contains 1.25µg Trimethoprim and 23.75µg Sulfamethoxazole per disc. - 25µg Total Antibiotic Content: Standardized combination in a 1:19 ratio. - Antimicrobial Susceptibility Testing: Designed for standardized agar disc diffusion procedures. - Sequential Folate Synthesis Inhibition: Combines two antimicrobial agents acting at different stages of bacterial folate metabolism. - Gram-Positive and Gram-Negative Testing: Supports investigations involving selected bacterial pathogens. - Consistent Antibiotic Diffusion: Manufactured for reproducible laboratory performance. - High-Quality Paper Discs: Impregnated with standardized concentrations of both antimicrobial agents. - Convenient Packaging: Five cartridges containing 50 discs each. - Compatible Disc Dispensers: Designed for use with suitable MAST antibiotic disc dispensers. - CLSI and EUCAST Catalogue Range: Listed by MAST under both standards. - Refrigerated Storage: Recommended storage temperature of 2–8°C. Specification Details Product Name Trimethoprim/Sulfamethoxazole Antibiotic Susceptibility Test Discs Brand MAST Product Range MASTDISCS Product Code TS25C Alternative Name Co-Trimoxazole Antibiotic Combination Trimethoprim/Sulfamethoxazole Antibiotic Class Antifolate Combination Trimethoprim Concentration 1.25µg per disc Sulfamethoxazole Concentration 23.75µg per disc Total Antibiotic Content 25µg per disc Concentration Ratio 1:19 Test Method Agar Disc Diffusion Pack Size 5 × 50 Discs Total Quantity 250 Discs Format Antibiotic-Impregnated Paper Discs Application Antimicrobial Susceptibility Testing Storage Temperature 2–8°C Package Dimensions 30 × 103 × 30 mm GTIN 15060392371579 Commodity Code 38229000 Minimum Order Quantity 1 Pack Regulatory Markings CE and IVDR Catalogue Testing Standards CLSI and EUCAST Intended Use In Vitro Diagnostic Laboratory Testing Manufacturer MAST Group